Case studies


ICNARC played a key role in establishing whether a new treatment protocol for critically ill patients with sepsis improved patient outcomes, both nationally and internationally.


ICNARC data provided linked outcomes for patients admitted to critical care for this vital clinical trial in COVID-19.

Canadian critical care nutrition guidelines

Additional analyses of data from the CALORIES trial supported guidelines on feeding critically ill patients.

Interventions to reduce mortality from in-hospital cardiac arrest

Data from the National Cardiac Arrest Audit were used in a mixed-methods research study to explore changes over time associated with the introduction of interventions aimed at identification and management of deteriorating patients.

Night discharge

A seminal early publication from the Case Mix Programme highlighted the pressure on critical care services in England, contributing to substantial increased investment. Subsequent monitoring as a quality indicator has shown improvements over time.