Publications

A list of FIRST-ABC’s publications can be found here.

Ramnarayan P, Richards-Belle A, Drikite L, Saull M, Orzechowska I, Darnell R, Sadique Z, Lester J, Morris KP, Tume LN, Davis PJ, Peters MJ, Feltbower RG, Grieve R, Thomas K, Mouncey PR, Harrison DA, Rowan KM. Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Therapy on Liberation From Respiratory Support in Acutely Ill Children Admitted to Pediatric Critical Care Units: A Randomized Clinical Trial. JAMA 2022; 328(2):162-72. http://dx.doi.org/10.1001/jama.2022.9615

Ramnarayan P, Richards-Belle A, Drikite L, Saull M, Orzechowska I, Darnell R, Sadique Z, Lester J, Morris KP, Tume LN, Davis PJ, Peters MJ, Feltbower RG, Grieve R, Thomas K, Mouncey PR, Harrison DA, Rowan KM. Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial. JAMA 2022; 327(16):1555-65. http://dx.doi.org/10.1001/jama.2022.3367

Richards-Belle A, Davis P, Drikite L, Feltbower R, Grieve R, Harrison DA, Lester J, Morris KP, Mouncey PR, Peters MJ, Rowan KM, Sadique Z, Tume LN, Ramnarayan P. FIRST-line support for assistance in breathing in children (FIRST-ABC): a master protocol of two randomised trials to evaluate the non-inferiority of high-flow nasal cannula (HFNC) versus continuous positive airway pressure (CPAP) for non-invasive respiratory support in paediatric critical care. BMJ Open 2020; 10(8):e038002. http://dx.doi.org/10.1136/bmjopen-2020-038002

Orzechowska I, Sadique MZ, Thomas K, Davis P, Morris KP, Mouncey PR, Peters MJ, Richards-Belle A, Tume LN, Ramnarayan P, Harrison DA. First-line support for assistance in breathing in children: statistical and health economic analysis plan for the FIRST-ABC trial. Trials 2020; 21(1):903. http://dx.doi.org/10.1186/s13063-020-04818-w

Ramnarayan P, Lister P, Dominguez T, Habibi P, Edmonds N, Canter RR, Wulff J, Harrison DA, Mouncey PM, Peters MJ. FIRST-line support for Assistance in Breathing in Children (FIRST-ABC): a multicentre pilot randomised controlled trial of high-flow nasal cannula therapy versus continuous positive airway pressure in paediatric critical care. Crit Care 2018; 22(1):144. http://dx.doi.org/10.1186/s13054-018-2080-3

Ramnarayan P, Lister P, Dominguez T, Habibi P, Edmonds N, Canter R, Mouncey PR, Peters MJ. FIRST-line support for Assistance in Breathing in Children (FIRST-ABC): protocol for a multicentre randomised feasibility trial of non-invasive respiratory support in critically ill children. BMJ Open 2017; 7(6). http://dx.doi.org/10.1136/bmjopen-2017-016181